Epidemiology of hepatitis C: related hepatocellular carcinoma in Cameroon

Epidemiology of hepatitis C: related hepatocellular carcinoma in Cameroon

Blog Article

INTRODUCTION: hepatocellular carcinoma (HCC) is a global public health problem.Hepatitis C virus (HCV) infection accounts for close to 24% of HCC in developing countries especially when associated with cirrhosis.There exists no vaccine against HCV to prevent the occurrence of HCV-related HCC.

A sound knowledge of the epidemiology and prevention of the initial infection is vital.The aim MELATONIN 5MG GUMMIES of our study was to determine the epidemiologic profile of HCV-related HCC in Cameroon to improve its management.METHODS: it was a prospective study of histologically proven HCV-related HCC seen in two University Centers in Yaounde, Cameroon from March 2012 to January 2013.

Demographic data (age, gender), alcohol abuse (=80g/day), presence of cirrhosis, tobacco abuse and parenteral exposition were analyzed.RESULTS: twenty-six patients with histologically proven HCV related HCC were included (18 men (69.2%) and 8 women (30.

8%); mean age +/- SD, 61.46+/-10.18 years).

A total of 22 (84.6%) patients had a parenteral exposition, 02 (7.7%) patients were alcoholics and 06 (23.

1%) patients were smokers.The proportion of patients with cirrhosis was 69.2% against 30.

8% cirrhosis-free.Patients with cirrhosis were relatively younger than DC Motor Set those cirrhosis-free (mean age +/- SD, 59.05+/-10.

05 years vs 66.87+/- 8.72 years, p=0.

06).HCV-related HCC was more prevalent in 60 years and above patients (53.8%, 95%CI: 33.

4-73.4).The relative risk of HCC among alcoholics patients was high (RR: 1.

5, 95%CI: 1.13-1.99, p=0.

05).